KPNA2 polyclonal antibody
产品名称： KPNA2 polyclonal antibody
英文名称： KPNA2 polyclonal antibody
产品编号： PAB19315
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody rasied against synthetic peptide of KPNA2.
- Immunogen:
- A synthetic peptide corresponding to 15 amino acids near N-terminus of human KPNA2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of KPNA2 in rat heart tissue lysate with KPNA2 polyclonal antibody (Cat # PAB19315) at (1) 1 and (2) 2 ug/mL.
- Entrez GeneID:
- 3838
- Protein Accession#:
- NP_002257
- Gene Name:
- KPNA2
- Gene Alias:
- IPOA1,QIP2,RCH1,SRP1alpha
- Gene Description:
- karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
- Omim ID:
- 600685
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq
- Other Designations:
- RAG cohort 1,importin alpha 1,importin alpha 2,importin-alpha-P1,karyopherin alpha 2,pendulin
- Related Disease