FITC标记的尿素转运型糖蛋白A2抗体
产品名称： FITC标记的尿素转运型糖蛋白A2抗体
英文名称： Anti-SLC14A2/FITC
产品编号： HZ-11801R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SLC14A2/FITC Conjugated antibody
FITC标记的尿素转运型糖蛋白A2抗体
| 产品编号 | bs-11801R-FITC |
| 英文名称 | Anti-SLC14A2/FITC |
| 中文名称 | FITC标记的尿素转运型糖蛋白A2抗体 |
| 别 名 | UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14 (urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 神经生物学 信号转导 通道蛋白 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 101kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC14A2/UT-A |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011] Function: Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism. Subunit: Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane. Subcellular Location: Apical cell membrane; Multi-pass membrane protein. Tissue Specificity: Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney. Similarity: Belongs to the urea transporter family. Database links: Entrez Gene: 8170 Human Entrez Gene: 27411 Mouse Entrez Gene: 54302 Rat Omim: 601611 Human SwissProt: Q15849 Human SwissProt: Q8R4T9 Mouse SwissProt: Q62668 Rat Unigene: 710927 Human Unigene: 44158 Mouse Unigene: 10157 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白属于脲转运蛋白家族。在哺乳动物细胞中，尿素是氮分解代谢的主要产物，在尿浓缩机制中起着重要作用。这种蛋白在肾内髓质中表达，并介导跨肾髓质集合管的快速跨上皮尿素转运。另外，已经发现这种基因的剪接转录变体。