Anti-CASP3 Polyclonal Antibody

品牌：solarbio | 货号：K001599P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001599P-50ul	solarbio	50ul	960.00元
K001599P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-CASP3 Polyclonal Antibody
别名 CPP32;CPP32B;SCA-1
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 32kDa
Gene ID 836
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CASP3
性状 液体
Public Immunogen Range A synthetic peptide of human CASP3
Subcellular Locations Cytoplasm
Swiss Prot P42574
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

英文名称	Anti-CASP3 Polyclonal Antibody
别名	CPP32;CPP32B;SCA-1
应用	WB IF
稀释比例	WB 1:500-2000. IF 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	32kDa
Gene ID	836
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human CASP3
性状	液体
Public Immunogen Range	A synthetic peptide of human CASP3
Subcellular Locations	Cytoplasm
Swiss Prot	P42574
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.