FITC标记的溶质载体家族蛋白22成员A2抗体
产品名称: FITC标记的溶质载体家族蛋白22成员A2抗体
英文名称: Anti-SLC22A2/FITC
产品编号: HZ-19806R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SLC22A2/FITC Conjugated antibody
FITC标记的溶质载体家族蛋白22成员A2抗体
英文名称 | Anti-SLC22A2/FITC |
中文名称 | FITC标记的溶质载体家族蛋白22成员A2抗体 |
别 名 | MGC32628; OCT 2; OCT2; Organic cation transporter 2; Organic cation transporter; RP11-317M22.2; Solute carrier family 22 (organic cation transporter) member 2; Solute carrier family 22 member 2. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 63kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC22A2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008] Function: SLC22A2 (solute carrier family 22 (organic cation transporter), member 2) is an organic cation transporter. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is found primarily in the kidney, where it may mediate the first step in cation reabsorption. It plays important roles in the renal tubular secretion of cationic drugs. Subcellular Location: Plasma membrane Similarity: Belongs to the major facilitator (TC 2.A.1)superfamily. Organic cation transporter (TC 2.A.1.19) family. Database links: Entrez Gene: 6582 Human Entrez Gene: 20518 Mouse Entrez Gene: 29503 Rat Omim: 602608 Human SwissProt: O15244 Human SwissProt: O70577 Mouse SwissProt: Q9R0W2 Rat Unigene: 436385 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在肝脏、肾脏、肠道和其他器官中的多特异性有机阳离子转运蛋白对于消除许多内源性小有机阳离子以及广泛的药物和环境毒素是至关重要的。该基因是位于6号染色体上的三个相似的阳离子转运蛋白基因之一。编码的蛋白质含有十二个假定的跨膜结构域,是一个血浆整合膜蛋白。两个不同的异构体编码两个不同的异构体已经发现了这个基因,但