FITC标记的RNA结合蛋白15B抗体
产品名称： FITC标记的RNA结合蛋白15B抗体
英文名称： Anti-RBM15B/FITC
产品编号： HZ-21289R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-RBM15B/FITC Conjugated antibody
FITC标记的RNA结合蛋白15B抗体
| 英文名称 | Anti-RBM15B/FITC |
| 中文名称 | FITC标记的RNA结合蛋白15B抗体 |
| 别 名 | 1810017N16Rik; Chromosome 3p21.1 gene sequence; HUMAGCGB; huOTT3; One twenty two protein 3; One-twenty two protein 3; OTT3; Putative RNA binding protein 15B; Putative RNA-binding protein 15B; RB15B_HUMAN; RBM15B; RGD1305937; RNA binding motif protein 15B; RNA-binding motif protein 15B. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 97kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RBM15B |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009] Function: May function in the regulation of alternative or illicit splicing. Subcellular Location: Nucleus > nucleoplasm. Colocalizes with BMLF1 in the nucleus. Localized in the nucleoplasm with a granular staining pattern and excluded from the nucleoli. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the RRM Spen family. Contains 3 RRM (RNA recognition motif) domains. Contains 1 SPOC domain. Database links: Entrez Gene: 29890 Human Entrez Gene: 109095 Mouse Entrez Gene: 315988 Rat Omim: 612602 Human SwissProt: Q8NDT2 Human SwissProt: Q6PHZ5 Mouse Unigene: 118738 Human Unigene: 431589 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SPEN(Sp.-end)蛋白家族的成员，包括RBM15B，在多个信号通路中具有抑制功能，并且可以通过与剪接体成分相互作用而与RNA结合(Hiriart等人，2005[PubMed 16129689])。